Welcome to an exploration of US Patent 6630507B1, which sheds light on the antioxidant and anti-inflammatory properties of cannabinoids. This patent, granted in 2003, unveils a groundbreaking avenue for treating various diseases, including neurodegenerative conditions like Alzheimer's. Despite its potential, legal hurdles and industry dynamics shape its impact on the medical cannabis landscape. Additionally, Rick Simpson Oil (RSO), a cannabis extract, has gained attention for its therapeutic applications, while ongoing research illuminates the diverse effects of cannabinoids.
Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention...
Phytocannabinoids Beyond THC & CBD
A May 2019 molecular biology study assayed eleven cannabinoids in a pre-clinical Alzheimer’s disease platform for their ability to remove intra-neuronal amyloid and neuroprotection. Nine of the 11 were able to remove intra-neuronal Ab, reduce oxidative damage and protect neuronal function...
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"What is RSO? In 2003, Rick Simpson created a cannabis oil after three suspicious bumps on his arm turned out to be basal cell carcinoma, a form of skin cancer."
What is Rick Simpson Oil? | Make & use RSO | Leafly
"Some years later, in 2003, Simpson was diagnosed with a form of skin cancer known as basal cell carcinoma. This led him to further explore marijuana as medicine. Simpson read a study from The Journal of the National Cancer Institute in which Tetrahydrocannabinol or THC (the main psychoactive cannabinoid in marijuana) was found to kill cancer cells in mice." "In the late 1990s, Simpson..."
"Making your own RSO at home is not difficult, and the process isn’t all that different from making cannabutter or other kinds of infused cannabis oil."
Rick Simpson Oil for Alzheimer's
“I think all we can say safely so far is using low doses of marijuana for prolonged periods of time at some point in your life, possibly when you’re middle-aged to late middle-aged, is probably going to slow the onset or development of dementia, to the point where you’ll most likely die of old age before you get Alzheimer’s." These were the words of Dr. Gary Wenk,Professor of Psychology & Neuroscience & Molecular Virology, Immunology and Medical Genetics at the Ohio State University and Medical Center."
"Despite what we have heard all our lives about how hazardous marijuana was to our brains, the evidence that has been emerging for the past decade strongly supports the use of marijuana or cannabis oil (Rick Simpson oil) as a catalyst to brain cell growth and a deterrent to fatal brain diseases and disorders."
Chairman Nadler Statement for the Markup of H.R. 3617, the MORE Act of 2021